Production Lead: Microarray Decoding

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Job description

Company Overview: Terray Therapeutics is a venture-backed biotechnology company leveraging our vast high-quality data to optimize the path from discovery to transformative therapeutics. Our approach delivers on the promise of computation to revolutionize drug discovery. Through our closed-loop wet lab discovery platform and data-rich AI, we overcome existing constraints on chemical data by systematically mapping the biochemical interactions of massive and diverse small molecule libraries to identify novel therapeutic compounds. Access to this quantitative data at scale allows us to intelligently navigate an infinitely extensible and highly diverse chemical space to efficiently design, discover and optimize small molecule therapeutics. Our internal development programs are focused on immunology. In addition to these programs we also work with leading pharmaceutical companies.

Our integrated computational platform, tNova, harnesses our novel affinity binding technology, tArray, unique resynthesis capabilities, and broad biology infrastructure. tArray is the foundation of our discovery engine. It enables us to screen hundreds of millions of compounds in minutes and return quantitative data on each compound. Vast, high purity, and high diversity compound libraries are rapidly iterated using best-in-class chemistry to unlock chemical insights at the scale necessary to power AI-driven drug discovery.

Position Summary: Terray Therapeutics is seeking a manager to lead our decoding team that supplies tArray with the ulta-dense microarray chips. This key decoding process identifies where each of the 32 million compounds is on each chip by sequencing the oligonucleotides at each position using custom automated and integrated fluidic/fluorescent imaging platforms.

The candidate will manage a small team dedicated to microarray decoding. The candidate will be responsible for supervising this team, the custom fluidic/imaging platforms, data processing and all necessary reagents and supplies to maximize production efficiency. The candidate will develop and monitor quality metrics used to QC the workflow throughout.

In addition to leading the decoding team, the candidate will work closely with the data team, the chemistry team and the automation team. The candidate will be a key member of Terray's production team, which also includes library synthesis and chip manufacturing, and will report to the head of Automation.

Experience and Qualifications: Given the company's size, anticipated growth and fast-paced environment, the organization requires a scientist who is thoughtful, high energy and can work effectively to further enhance our next generation drug discovery capabilities.

Part of Terray Therapeutics' success is nurtured by a hands-on work environment where everyone is accountable, everyone is vested in a vision of excellence, and everyone actively takes part in the success of the business. Terray Therapeutics supports a positive work environment comprised of engaged employees who feel appreciated, recognized and free to be creative.

Required Qualifications:

• Master's degree in Biology, Chemistry, or related disciplines; or
• Bachelor's degree in Biology, Chemistry, or related disciplines AND 3 years experience working with oligonucleotides, imaging technologies and/or microarrays post-degree
• Solid demonstrated experience managing a team in a scientific production/manufacturing environment
• Excellent attention to detail
• Strong written and verbal communication and interpersonal skills
• Desire to be a team player in a cross-functional environment

Preferred Qualifications:

• Experience with fluorescence microscopy
• Experience with microfluidic systems
• Experience with large datasets
• Experience with oligonucleotides

She/he will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.