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Principal Scientist II (Team Lead)
Roche
2021-12-03 07:35:08
Pleasanton,
California,
United States
Job type: fulltime
Job industry: Science & Technology
Job description
You will be a member of the molecular lab RUO/LDT and Pharma Services team based in Pleasanton focused on research and early development of robust prototype assays that will have a direct impact on our Pharma Partnering business.
The successful candidate will lead, develop, and implement R&D workflows for related NGS applications in hematologic and solid tumor oncology to begin with and then branch out to areas including neuroscience and rare diseases.
Responsibilities:
- Leads, coaches and mentors a team of Scientists and Sr. Scientists in the design, planning and execution of assigned research and prototype assay generation. Performs hand-on research activities at the bench.
- Independently defines and plans project goals, and achieves them with the help of the team. Makes recommendations, and when appropriate, acts independently to resolve scientific problems encountered during experimental procedures. Ensures activities are consistent with project critical path, and responds appropriately to changing priorities.
- Accurately, consistently, and promptly records experimental methods, materials and results in electronic laboratory notebooks. Analyzes data, evaluates results, forms conclusions and implements/documents process improvements.
- Integrates previous and current results to determine next experimental steps and the impact on long-term project goals.
- Guides team members to the planning, prioritization, execution and analysis of experiments, and helps them analyze and interpret results, generate reports, troubleshoot problems and formulate solutions based on scientific knowledge and past experience.
- Presents findings at group or departmental meetings. Applies advanced technical writing skills to produce reports and documents. Prepares summaries, memos, internal reports, presentations, manuscripts, etc.
- Collaborates with and serves as a resource to other functions (e.g., Development, Operations, Quality, Marketing, Regulatory Affairs, Clinical Operations, CAP/CLIA lab and Bioinformatics), provides timely response and follow-ups. Participates in the expeditious transfer of products and technologies by providing scientific knowledge and assistance.
- Work involves troubleshooting and resolving difficult problems in creative ways. Takes a new perspective on existing solutions, exploring and implementing new concepts and methodologies.
- Ensures on time completion of contractual obligations with our partners
Qualifications:
- Master's degree (PhD preferred) in Biological,/Life Sciences, Biochemistry or related field. 6+ years of relevant experience.
- Experience in leading and mentoring teams.
- Knowledge and experience in experimental design, data analysis, and data and concept presentation.
- Hands-on experience in next-generation sequencing, e.g. Illumina, Ion Torrent, or PacBio platforms
- Experience with various types of clinical specimen and sample types for use in molecular assays, including purified DNA, fresh and FFPE tissue material, blood, purified cells, etc.
- Strong communication and organization skills.
- General molecular biology hands-on skills.
- Hands-on experience with both qPCR and dPCR
- Experience in verification / validation experimental design, statistical data analysis and interpretation.
- Experience in oncology, neurology, or rare disease NGS assay development
- Experience writing SOPs
Travel Requirements:
- 15% base on business needs
Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law. If you have a disability and need an accommodation in connection with the on-line application process, please email us at .
- Who we are
At Roche, 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.