Sr. Mechanical Engineer - Bioprocessing Consumables

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Job description

Xcellbio is an venture-backed immuno-oncology focused technology startup based in San Francisco. Our rapidly growing company has had success in raising multiple financing rounds from some of the top venture capital names in the industry. Our mission is to enhance the performance and safety of cell and gene therapies through the design and development of a suite of innovative technology platforms. Our commercial instruments and AI-driven software enable researchers to discover novel insights into immune and tumor biology. Our product development team is working to translate these insights at patient-scale, through the development of a novel cell therapy manufacturing technology. We are focused specifically on the cell therapy processing unit function of cell maintenance and expansion to leverage our unique IP positioning and know-how to improve therapeutic potency and persistence during the manufacturing process. Our fun, well-capitalized, and mission-driven team is expanding several fold in the near-term - now is a great time to join and a great time to lead our technology driven organization!

Description of Position:
We are looking for a creative, engineering and process-minded individual with recent experience in product and/or process development within the cell and gene therapy manufacturing space to join our recent Series B-funded high growth startup as a Sr. Hardware Engineer with a focus on plastics/consumables. This individual will have a key role in supporting our cell therapy manufacturing technology development for an industry-leading manufacturing system
for personalized/autologous cell therapies. You will have ownership of specific subsystem designs through beta prototype creation. An ideal candidate will have direct experience in working on consumables for bioprocessing (e.g., gas permeable bags, tubing, plastics) and some familiarity with current hardware technologies and workflows serving the immune cell therapy market (e.g., Miltenyi, Lonza, Cytiva). In this role, you will engage in all facets of product development including concepting, documentation, design, prototyping and transfer to manufacturing. The candidate must have the drive to solve complex technical problems, work in a fast-paced environment, across multiple stakeholders and subject matter experts.

Key Responsibilities:
- Evaluating and testing consumables associated with cell therapy (e.g., gas permeable bags, tubing, plastics).
- Collaborate with a diverse group of engineers, biologists, software designers, end-users and external suppliers
- Participate in the translation of user and functional requirements to design specification, concepts and direction
- Execute project scope throughout the conception, design and pilot phases
- Generate and review documentation required for manufacturing technical transfers
- Support of activities pertaining to market-readiness of product, including qualification activities.

Education, Experience, and Skill Requirements:
- Masters or Bachelor's in Mechanical Engineering or related field with emphasis on CAD design and prototyping
- 5+ years of experience working in a company that designs and/or manufactures biotech consumables. Preference for biotech, bio-chemistry, or chemical engineering equipment
- Direct experience with developing consumables for the biotech space
- Candidates with direct domain experience in immune cell therapy processing and manufacturing workflows will be given priority
- Highly motivated self-starter who can prioritize and take ownership of tasks
- Excited to be "hands-on" in solving product problems
- Must be comfortable in a rapidly growing and evolving start-up environment
- Please note if you are legally authorized to work in the United States in your application