Associate Scientist / Senior Research Associate / Research Associate, Preclinical Development

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Job description

Associate Scientist / Senior Research Associate / Research Associate, Preclinical Development

Nura Bio is a venture-backed biopharmaceutical company located in South San Francisco, CA. At Nura Bio, we are transforming recent scientific breakthroughs in axonal degeneration and neuroimmune regulation into neuroprotective medicines to offer renewed hope for those affected by serious neurological diseases.

We are looking for a highly motivated Associate Scientist / Senior Research Associate / Research Associate to join the biology team. In your role, you will be focused on preclinical neurodegenerative disease model development and the establishment of medium throughout primary neuron-based culture systems to support the evaluation novel neuroprotective compounds. The exact level of your role will be commensurate with your experience. As a member of the Nura Bio team, you will be part of a culture of scientific excellence, rigorous innovation, collaboration, and fun! We offer exciting professional growth opportunities, highly competitive compensation, equity, and a generous benefits package.

Key Responsibilities:

• Develop, design, and execute in vivo studies in a range of rodent neurodegenerative disease models with functional, histological, and biomarker endpoints to support target mechanism of action, evaluation of PK/PD relationships, and preclinical efficacy of novel therapeutics
• Develop, design, and execute in vitro primary neuron assays with multiple analytical endpoints including, but not limited to, live imaging, stained/fixed cell imaging, and protein or metabolite quantification
• Analyze data, interpret, and communicate results
• Keep detailed and organized records of experimental protocols and results
• Rely upon your keen analytical and problem-solving skills to troubleshoot technical issues and implement solutions
• Keep current with scientific literature relating to neurodegeneration

Professional Experience/Qualifications:

• A Bachelor's or Master's degree in Biology, Biochemistry, Molecular Biology, or related field with 4+ years of hands on research experience in neuroscience in an industrial or academic setting
• Demonstrated proficiency with preclinical animal models: handling, husbandry and colony management, genetic tools, drug or viral delivery, tissue and fluid collection, surgical techniques, and behavioral assays with a focus on neurological function
• Experience collecting and preparing CNS/PNS tissue (cryostat sectioning, staining, immunohistochemistry) for microscopy and developing unique analyses for timely data collection
• Experience with primary neuronal tissue culture and cell-based assay development is required
• Keen analytical and problem-solving skills, and the ability to resolve complex problems requiring innovative, custom solutions
• Ability to independently analyze and interpret data (e.g., GraphPad Prism, Origin, R, etc.)
• Demonstrated ability to multi-task and meet aggressive deadlines

If you have the experience we are seeking and would like the opportunity to contribute to our mission, we would like to hear from you! Please send your CV with a cover letter delineating why you are interested to join Nura Bio.

Nura Bio is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

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