Research Associate/Senior Research Associate, Biology

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Job description

About IDEAYA Biosciences:
IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage synthetic lethality-focused precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics. Our approach integrates extensive capabilities in identifying and validating translational biomarkers with small molecule drug discovery to select patient populations most likely to benefit from the therapies we are developing. We are applying these capabilities across multiple classes of precision medicine, including direct targeting of oncogenic pathways and synthetic lethality - which represents an emerging class of precision medicine targets. We believe this diversified approach will enable us to deliver the right medicine to the right patient to drive a more robust clinical response.
IDEAYA recently announced a landmark strategic partnership with GSK in Synthetic Lethality for certain pipeline programs. The GSK partnership is transformative and enables IDEAYA and GSK to collectively build an industry leading platform and pipeline in Synthetic Lethality. For more information, please see .

The Opportunity:

We are seeking a highly motivated and detail-oriented laboratory-based Research Associate/Senior Research Associate in the Biology group. The candidate will be responsible for designing, executing, and analyzing cell-based assays to understand the mechanism of action and pharmacodynamic properties of our oncology drug candidates. As a key member of a multi-disciplinary team, the successful candidate will demonstrate scientific curiosity, excellent communication skills, and effective multi-tasking. The position level will be commensurate with experience.

What you'll do:

•Design in vitro cell-based experiments under general supervision, independently perform experiments, and analyze and interpret scientific findings with general supervision
•Execute and troubleshoot assays to support mechanism of action and pharmacodynamic studies using mammalian cell culture, western blot, ELISA, RT-qPCR, and flow cytometry
•Develop and validate new assays to support clinical biomarker assays
•Present data and project statuses regularly at departmental research meetings
•Collaborate with Chemistry and Lead Discovery departments to characterize our lead compounds

Requirments - AKA What you'll Bring:

• BS/MS degree in cancer, cell, molecular biology, or related discipline, with 2+ years of research experience, preferably in industry setting
• Expertise in cell and molecular biology techniques, such as mammalian tissue culture, western blot, ELISA, nucleic acid isolation, and RT-qPCR, and data analysis/visualization software
• Familiarity with flow cytometry, siRNA transfection/shRNA transduction, or MSD is a plus
• Experience with assay design, optimization, and troubleshooting
• Self-motived, demonstrates aptitude for independent critical and creative thinking, and demonstrates scientific interest behind the experimental objective
• Strong interpersonal skills and effective written and oral communication with cross functional teams
• Ability to multi-task and adapt to shifting priorities and timelines, while maintaining high attention to detail

The Company complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite at the Company's facilities and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.

Benefits
When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward.

Ideaya is an equal opportunity employer. In accordance with applicable law, Ideaya does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.