Sr. Scientist, Cell Therapy

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Job description

Sr. Scientist, Cell Therapy
Cambridge, MA

Summary
Seeking an innovative and experienced scientist to join the ex vivo pharmacology team to develop Client cell-based medicines utilizing proprietary gene editing platform.

Responsibilities

• Analyze current scientific literature to propose new approaches and to design and create the next generation cell therapy platform, specifically in iPSC-derived or HSC-derived therapeutics
• Develop project strategy, understand timeline and deliverables, plan and coordinate project work with functional stakeholders
• Lead and execute activiteis to build process to generate cell therapy products
• Develop molecular and cellular assays to characterize the identity, purity, and potency of cell therapy products
• Collaborate with in vivo pharmacology team to perform in vivo proof-of-concept studies
• Interact with clinical development and manufacturing teams to plan and conduct IND-enabling studies internally and at CRO
• Manage CROs and academic collaborators
• Present data internally and at scientific conferences
• Establish SOPs, write prospective protocols, author study reports and regulatory documents, assist patent filing
• Serves as a technical and scientific resource for junior staff

Qualifications

• PhD in stem cell biology, immunology, pharmacology, or related disciplines with a minimum of 6 years of academic or industry experience
• Process broad knowledge of current concepts in cell and gene therapy
• Experience in developing iPSC-derived or HSC-derived cell therapy products
• Analytical and problem-solving skills
• Skilled in cell culture, development of molecular and cellular assays, and handling of small laboratory animals
• Experience in managing direct reports
• Familiarity with FDA and EMA guidance for cell and gene therapy; experience with IND-filing preferred
• Ability to conduct high-quality resaerch and execute research plans in a timely and organized manner
• Ability to work independently and collaborate effectively with cross-functional team in a fast-pace and dynamic environment to meet project goals under a tight timeline
• Driven, enthusiastic, and self-motivated
• Excellent time management and prioritization skills to manage multiple tasks simultaneously
• Strong technical, written and communication skills

Company Description:

About Ascent:

Ascent is a leading national technology consulting and professional services firm that focuses on tactical and strategic consulting. Ascent's fundamental business is providing staffing services to Large Enterprise clients in our core market verticals: Financial Services, Healthcare, and Life Sciences. We focus the majority of our efforts in Staff Augmentation support of Large Enterprise Clients who utilize a Vendor Management System. Ascent works as both a reliable supplier in support of programs, as well as a Strategic Advisor in support of enterprise efforts to establish best in class preferred vendor programs. Ascent was ranked in the 2007 and 2008 Inc. 500 and recognized specifically for its innovative work in staff augmentation support of Large Enterprise preferred vendor accounts.

If you are ready to propel your career to new heights… read on. We are looking for talented and dedicated colleagues to join our phenomenal team. At Ascent, we have created an environment where culture, commitment and opportunity converge to yield a truly unique place to work. We know that every employee has something important to say and that every employee is integral to our success. Where else can you walk over to a founder and talk about your ideas to help build our business and have that idea implemented in 48 hours? More importantly, we do everything we can to make sure our employees not only have great jobs, but great lives.