Research Associate-Cell or/Molecular biology

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Job description

Job Title : Research Associate - Biology

Location: Waltham, MA

Duration: months extendable contract

Minimum Qualifications

BS with 1 years of experience in a relevant scientific area or MS in cell biology, oncology, immunology, or related subject

Familiarity with culturing cell lines of diverse lineages as well as deriving and maintaining cell lines

Hands-on experience with techniques pertaining to molecular and cellular biology (e.g., PCR, RT-PCR, western blotting, ELISA, cell staining/flow cytometry, cytotoxicity assays, intracellular protein interaction assays).

Conducts experiments after discussion of the design and strategy with the supervisor.

Contributes to assay development, optimization and validation.

Performs literature searches and analysis as needed for assay development.

Experience in Biochemical/cell-based assay development using a variety of techniques such as FRET, MSD, HTRF, ALPHALisa based readouts is preferred but not required

Develop mechanism-based in vitro assays involving primary human immune cells to drive drug discovery with the support of supervisor

The successful candidate must be detail orientated and have the ability to work independently while also being a team player

Job Description

This position will be an integral part of the in vitro pharmacology group and the ideal candidate will help drive assay support in disease areas with a primary focus in oncology.

This is predominantly a laboratory/wet bench-based role and requires strong attention to details, ability to deliver quality data in a timely manner and work effectively with team members, both internal and external (CRO) in support of client

The candidate will support routine cell-based assays for compound profiling and deliver with the support of supervisor in vitro 'proof of concept' work for targets of interest. As well as part take in the development of phenotypic and mechanistic assays using cutting edge technologies to support screening cascades and/or prosecuting functional roles of targets in secondary assays of biological relevance e.g., human primary tumor tissues. Familiarity with disease mechanisms in Oncology and Immuno-Oncology is preferred.

Data analysis, interpretation, documentation and presentation skills is required.