Scientist, Antibody Discovery - Bioassay
Just - Evotec Biologics
2021-12-03 07:37:41
Seattle, Washington, United States
Job type: fulltime
Job industry: Science & Technology
Job description
Just is seeking a highly motivated and creative Scientist that desires a significant opportunity to help invent the technologies required to improve worldwide access to biotherapeutics. This position will be part of a cross-disciplinary team discovering therapeutic antibodies from display libraries and optimization campaigns. The successful candidate will support the invention, design, and implementation of cell-based, functional bioassay and immunoassay methods to drive biotherapeutic development. A strong foundation in assay development and cell biology is required for this position, with additional experience in antibody discovery, target validation, in vivo PK models and automation preferred. This individual must also possess strong communication and collaboration skills, a desire to learn new scientific concepts and domains, and an ability to work directly with scientific staff across multiple disciplines.
Responsibilities:
- Work independently and in teams to develop, implement, and routinely execute cell-based bioassays such as reporter, proliferation, signaling, internalization, immunogenicity and immunoassays
- Perform mammalian cell culture, transient and stable cell line protein expression
- Routinely utilize FACS, plate spectrophotometers and other appropriate instrumentation
- Analyze, organize, summarize, and present data and results at department and project team meetings
- Stay informed of science and technology developments in the field and suggest process improvements to team
- Maintain a detailed and organized record of experiments in an electronic notebook
Qualifications and Education Requirements:
- B.S./M.S. degree in life sciences, cellular biology/immunology, or other related discipline with 5-10 years of relevant experience
- Experience with tissue cell culture, immunoassays and cell-based functional assays
- Excellent verbal and written communication skills
- Strong focus on quality and attention to detail
- Possess effective task/time management organizational skills
- Ability to work in small groups as well as independently
Preferred Qualifications:
- Experience in antibody discovery processes
- Experience with liquid handling automation
- Experience with protein binding kinetic assays (BLI, SPR)
- Familiarity with target validation for antibody discovery, in vivo efficacy and PK models
About Just - Evotec Biologics
Just - Evotec Biologics, wholly-owned by Evotec SE, is a unique platform company that integrates the
design, engineering, development, and manufacture of biologics. With deep experience in the fields of
protein, process and manufacturing sciences, the Just team came together to solve the scientific and
technical hurdles that block access to life-changing protein therapeutics; from the design of therapeutic molecules to the design of the manufacturing plants used to produce them. Just's focus is to create access and value for a global market through scientific and technological innovation. Our state-of-the-art labs and cGMP clinical manufacturing plant are co-located in Seattle's South Lake Union neighborhood - the center of Seattle's medical, global health, and technology industries and a noted top emerging life science hub in the U.S. Our fast-growing team of 100 employees is expanding Just's innovative platform and footprint - building our first North American J.POD® commercial manufacturing facility in the Seattle area.
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