Bioassay Scientist

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Job description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to over 50,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services, as one of the leading global emerging players in specialised clinical diagnostics testing.

In 2019, Eurofins generated total revenues of EUR € 4.56 billion, and has been among the best performing stocks in Europe over the past 20 years.

Eurofins DiscoverX Products, LLC is a leader in providing innovative solutions to the pharmaceutical industry by developing, manufacturing, and commercializing cell lines, cell-based assay kits, and supporting reagents. The holder of this position will be responsible for development of new cell lines and bioassays to support product development and client-driven custom projects.

* Responsible for manufacture and optimization of assay-ready cells to support development of custom bioassays for diverse DiscoverX assay formats.
* Participates as one of several analysts to perform assay qualification of custom bioassays with client therapeutic agent, generating the required data within timelines defined by client
* Reviews own assay qualification (or other experimental) results and confirms accuracy before submitting to supervisor / project lead for inclusion in study results / reports
* Provides appropriate documentation and technical support for downstream users of custom bioassays including contribution of detailed protocols for user manuals, custom methods, and/ or client reports.
* Provides detailed cell lot manufacturing / cell culturing information to operations team, and trains others to perform assay-ready cell manufacturing as needed
* Performs new assay development as needed to facilitate rapid development of novel assays for Eurofins DiscoverX product portfolio or custom development projects
* Presents results in both written and oral format and delivers data and/or reports to appropriate stakeholders within a multidisciplinary team environment in a timely fashion
* Accurately documents experimental procedures and results in the ELN and stores data on appropriate secure data servers in accordance with company policy
* Performs other duties as assigned to support the smooth functioning of shared laboratory spaces and equipment
* Provides cross-functional support to other departments as required
* Demonstrates and promotes the company vision
* Owns the accountability and responsibility of delivering to client needs and timelines
* Adjusts work hours as needed to meet client deadlines
* Regular attendance and punctuality
* Applies quality principles in all areas of responsibility, as appropriate
* Conducts all activities in a safe and efficient manner, adhering to site employee health and safety (EHS) requirements

The ideal candidate would possess:

* Experience with flow cytometry for characterization of surface markers strongly preferred
* Experience handling or isolation/purification of immune cells (e.g. PBMCs, NK and CD4+ / CD8+ T cells) desirable
* Experience performing quantitative target cell killing assays (e.g. ADCC, CDC, and T- cell redirection) desirable
* Experience with data analysis packages such as SoftMaxPro/PLA module or PLA 3.0 for parallel line analysis strongly preferred

Basic Minimum Qualifications:

* BS/MS in cell biology, biochemistry, biotechnology or related field with a minimum of 6 years of industry experience.
* Extensive mammalian cell culture expertise with including HEK, CHO and U2OS, as well as diverse cancer cell models
* Assay development expertise with various functional assay readouts (e.g. cAMP, reporter gene assays, etc.)
* Experience running or developing bioassays for potency or lot release applications strongly preferred
* Experience with data analysis packages such as GraphPad Prism, Microsoft Powerpoint and Excel required
* Ability to work independently, efficiently and productively in a fast-paced, highly collaborative and diverse team environment.
* Eagerness to develop, learn and adopt new methods
* Strong collaborative and communication skills, proactive attitude and critical problem-solving abilities
* Must be detail oriented and consistent in experimental approach.
* Demonstrated written and verbal communication skills.
* Highly organized, efficient and able to multitask.
* Authorization to work in the United States indefinitely without restriction or sponsorship

Position is full-time, Monday - Friday 8:00am-5:00pm. Candidates currently living within a commutable distance of Fremont, CA are encouraged to apply.

* Excellent full time benefits including comprehensive medical coverage, dental, and vision options
* Life and disability insurance
* 401(k) with company match
* Paid vacation and holidays

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.