Associate Scientist, Protein Sciences

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Job description

**Kelly Science and Clinical** is the world's most recognized brand in science and clinical staffing with more than 100 locations in North America, Europe, and the Pacific Rim. Our scientists contribute to the research and development of the next generation of small molecule drugs, biologics and cellular therapies.

**Overview**

We are seeking an Associate Scientist, Protein Sciences for one of our clients, a start-up biotech company in South San Francisco that is developing therapeutic antibody candidates to tackle multiple neurodegenerative diseases. The successful candidate will be responsible for the design, expression, purification, and biophysical characterization of novel antibody-effector fusion proteins that modulate inflammation for the treatment of human diseases. Our client is located in Lilly Gateway Labs in South San Francisco. This brand-new facility is designed specifically for early-stage biotech companies and offers a dynamic work environment. This position reports to the Director of Protein Chemistry and Analytics.

**Responsibilities**

+ Contribute to the engineering and production of new antibodies, novel antibody formats and antibody-fragment fusions with various effector modalities.

+ Production of recombinant proteins up to liter scale from mammalian cell lines (e.g., CHO cells and HEK cells) using standard purification methods (e.g., affinity chromatography, size exclusion chromatography, ion exchange chromatography, etc.)

+ Perform characterization on key reagents using protein analytical techniques (e.g., SDS-PAGE, HPLC chromatography, Octet, Western Blot, etc.)

+ Perform data analysis and summarize experimental results, with supervision as appropriate

+ Prepare and maintain cell culture reagents and media

+ Ensure sufficient laboratory supplies for daily laboratory operations

+ Generate, collect, analyze data and present scientific findings at internal research meetings

+ Collaborate with internal scientists and external collaborators to optimize batch production as applicable

+ Ensure proper operation and perform routine maintenance of laboratory equipment

+ Assist other staff to complete laboratory tasks, as necessary

+ Maintain a clean and safe work environment

**Qualifications**

+ Bachelor's degree in Biochemical, Chemical, or Biology related disciplines with 5 years of relevant experience, or a Master's degree with 3 years relevant experience.

+ Experience in engineering, productions, and characterization of protein and antibody variants as preclinical leads.

+ Background in protein chemistry and protein structure and function is required.

+ Experience with growth and transfection of mammalian cells up to liter scale for transient and/or stable protein production is required.

+ Laboratory experience in protein purification techniques and analytical/characterization methods is required.

+ Background in immunology/inflammation/neuroinflammation is preferred.

+ Pharma/biotech experience is preferred.

+ Experience working in a cross disciplinary environment is preferred.

+ Excellent English oral communication skills in a scientific setting are required.

+ Excellent technical writing skills and ability to prepare written reports.

+ Strong data analysis skills and excellent organizational skills.

+ Proficiency in Microsoft Office Programs.

\#TJP2021_SPEC

**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.

**Why Kelly** **®** **?**

Kelly® Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interests-it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.

**About Kelly** **®**

At Kelly, we're always thinking about what's next and advising job seekers on new ways of working to reach their full potential. In fact, we're a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.

Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. ()

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