RA/Sr.RA, Upstream Process Development (Tustin, CA)
Kelly Services
2021-12-03 09:01:56
Tustin, California, United States
Job type: fulltime
Job industry: Science & Technology
Job description
Research Associate or Sr. Research Associate, Upstream Process Development
Tustin, CA
Direct-Hire
Position Summary:
The Research Associate will assist process development in developing and optimizing scalable processes with improved product yield and reduced costs for manufacturing systems. This is a full-time, direct-hire position with a schedule of Mon-Fri 8 AM - 5 PM.
Essential Functions:
+ Responsible for mammalian cell culture process development to produce recombinant proteins, media screening, adaptation to suspension, adaption to serum free, comparing growth and productivity in various media, growing and maintain cells in T-flasks, spinner flasks and shake flasks.
+ Work with many different kinds of mammalian cell lines, and apply a good understanding of the effect of general metabolic pathways (nutrient usage, expression system, etc.) physical (morphology, pH, osmolality, etc.) as well as mechanical (column, agitation speeds, oxygen and pH control, etc.) parameters on cell growth and production.
+ Operate and troubleshoot cell culture equipment such as bioreactors and analyzers; and optimize lab/pilot/manufacturing scales and process/tech transfer to the Manufacturing department.
+ Research and implement new methods and technologies to enhance operations, clarification filter sizing, culture media and supplement/feed preparation, utilize aseptic techniques, analyze growth, production and nutrient usage data, create data spreadsheets in Excel, document data and findings for traceability and regulatory requirements, write technical and summary reports, and lastly, communicate findings and participate in group meetings.
Required Education and Experience:
+ The Research Associate position requires a BS degree in Biological Science. Minimum of 1 to 2 years of relevant industry experience with demonstrated working knowledge of scientific principles highly preferred.
+ Intermediate to advanced knowledge of Microsoft Excel, Microsoft Word, Microsoft Outlook and PowerPoint
+ Chemical or biological lab experience is highly preferred.
**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.
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