Sr. Research Associate / RA, Process Development (Upstream) - Irvine CA

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Job description

Sr. Research Associate / RA, Process Development (Upstream) - Irvine CA

Summary/Objective: The Research Associate will assist process development in developing and optimizing scalable processes with improved product yield and reduced costs for manufacturing systems. In addition, the Research Associate may assist with the maintenance of production equipment and may research and implement new methods and technologies to enhance process operations.

Essential Functions:

• Responsible for mammalian cell culture process development to produce recombinant proteins, media screening, adaptation to suspension, adaption to serum free, comparing growth and productivity in various media, growing and maintain cells in T-flasks, spinner flasks and shake flasks.
• Work with many different kinds of mammalian cell lines, and apply a good understanding of the effect of general metabolic pathways nutrient usage, expression system, etc. physical morphology, pH, osmolality, etc. as well as mechanical column, agitation speeds, oxygen and pH control, etc. parameters on cell growth and production.
• Operate and troubleshoot cell culture equipment such as bioreactors and analyzers; and optimize lab/pilot/manufacturing scales and process/tech transfer to the Manufacturing department.
• Research and implement new methods and technologies to enhance operations, clarification filter sizing, culture media and supplement/feed preparation, utilize aseptic techniques, analyze growth, production and nutrient usage data, create data spreadsheets in Excel, document data and findings for traceability and regulatory requirements, write technical and summary reports, and lastly, communicate findings and participate in scientific discussions within the group.
• Perform other duties as assigned.

Required Education and Experience:

• B.S. degree in Biological Science
• 1-2 years of relevant industry experience with demonstrated working knowledge of scientific principles.

For immediate consideration apply today!

Questions? Please reach out to Dustin at

#TJP2021_SPEC

You should know: Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.

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