Organic/Oligonucleotide Chemist

Role Summary

This Chemist role has a high emphasis on phosphoramidite synthesis, improving processes for synthesis of oligonucleotides, production of other reagents in support of oligo production, and other chemistry related duties.

Essential Responsibilities

• Duties include (but are not limited to):
• Synthesizing phosphoramidite monomers
• Identifying and developing processes for the synthesis, purification, and analysis of oligonucleotides and resolving technical challenges and difficulties
• Delivering new and custom products and involvement in tech transfer and scale-up of oligonucleotides
• Operating analytical equipment: UHPLC, HPLC, ESI-MS, UV-Vis, NMR
• Organizing work and recording all procedures accurately and consistently with notebooks and batch records
• Evaluating and extending new chemistries as well as providing innovations which can be developed into new product advantages

Quality Specific Goals:

• Aware of and comply with the Horizon Discovery Quality Manual, Quality Management System, Quality Management Policy, Quality Goals, and applicable laws and regulations as they apply to this job type/position
• Complete all planned Quality & Compliance training within the defined deadlines
• Identify and report any quality or compliance concerns and take immediate corrective action as required
• Support compliance/closure of Regulatory and Quality requirements before completing Design Outputs/Program Deliverables
• Participate in continuous improvement activities by identifying and appropriately escalating process and product quality gaps, providing solutions when possible

Qualifications/Requirements

• Bachelor's degree in Chemistry or related field with 5+ years relevant work experience, Masters degree in Chemistry or related field with 2+ years relevant work experience; or PhD in Chemistry or related field with 0 years of relevant work experience.
• Strong organic chemistry experience is highly desired; Experience in the synthesis of phosphoramidites is preferred
• Experience in developing processes for purification and analysis of large macromolecules is a plus
• Demonstrated problem solving ability
• Good oral and written communication skills

We can offer a varied and interesting working environment and as a growing company we are focused on recognition and empowerment of our scientists. We are committed to high quality science to meet our client and growth needs. In addition to competitive salaries we can offer an attractive flexible benefits package.

Compensation range

$85,000 - 105,000, depending on experience.

Benefits

• Comprehensive medical, dental, and vision coverage
• Flexible Spending Account - healthcare and dependent care
• Retirement 401(k) with employer match
• Paid time off and holidays

Horizon Delivers inspired solutions that harness the power of the cell. We are global leaders in cell engineering. Our vision is to unlock the power of the cell, and we are increasing our focus on customers everyday. Our unique tools and services are used by our customers to provide valuable insights and applications in - research, drug discovery, molecular diagnostics and biomanufacturing.

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We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

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