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Research Analyst

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University of Chicago

2021-12-03 08:58:11

Job location Chicago, Illinois, United States

Job type: fulltime

Job industry: Science & Technology

Job description

Department

BSD OBG - Lengyel Lab

About the Department

The ovarian cancer research laboratory was established at the University of Chicago in 2004. Our main goals include: 1. Understand the early steps of ovarian cancer metastasis to the peritoneum and omentum 2. Characterize tumor - stroma interactions in ovarian cancer, including the communications between adipocytes, fibroblasts, mesothelial cells, and cancer cells 3. Identify new treatment targets and evaluate the efficacy of these therapeutics in pre-clinical models to prepare for their translation into the clinic 4. Investigate the validity of agents that are effective treatments in other cancers to delay or inhibit the development of ovarian cancer 5. Utilize advanced proteomic and genomic analysis methods to gain further insights into ovarian cancer biology and develop tools for ovarian cancer detection and treatment This at-will position is wholly or partially funded by contractual grant funding which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.

Job Summary

The job performs routine assignments related to scientific research projects. Ensures compliance of research activities with institutional, state, and federal regulatory policies, procedures, directives and mandates. Analyzes possible solutions using standard procedures. Writes articles, reports and manuscripts. Assists in drafting presentations on research findings. The ovarian cancer research laboratory is looking for a Research Analyst to join its ovarian cancer research team. Specifically, the Research Analyst will be investigating the role of and therapeutic targets of the stroma during ovarian cancer disease progression, and will involve human tissue, in vivo mouse models, three-dimensional organotypic, and primary cell models to perform translational research. The Research Assistant will work collaboratively with the principal investigators, fellows, students and other research specialists. Under limited direction, the incumbent performs complex lab and/or research-related duties and tasks.

Responsibilities

* Assists with planning, development and execution of research in the laboratory.
* Aids in organizing the laboratory.
* Works collaboratively with the team and collaborators.
* Facilitates the management of animal colony and animal experiments.
* Conducts periodic training for current and new members of the laboratory.
* Contributes to the writing of academic papers, reports and final summaries.
* Collects, records, and analyzes data.
* Conducts literature reviews.
* Ensures compliance with institutional, state, and federal regulatory policies, procedures, directives, and mandates.
* May serve as a lead research specialist.
* Presents research findings at staff meetings, seminars, and scientific conferences.
* Maintains technical and administrative support for a research project.
* Analyzes and maintains data and/or specimens. Conducts literature reviews. Assists with preparation of reports, manuscripts and other documents.
* Installs, sets up and performs experiments; interacting with students and other laboratory staff under the direction of the principal investigator.
* Maintains recruiting and scheduling research subjects; assisting with developing or amending study protocols; assisting with developing data collection tools; assisting with building databases; and providing general administrative support. Has general awareness in research techniques or methods, regulatory policies and procedures, and relevant scientific field.
* Performs other related work as needed.

Minimum Qualifications

Education:

Minimum requirements include a college or university degree in related field.

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Work Experience:

Minimum requirements include knowledge and skills developed through
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Certifications:

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Preferred Qualifications

Education:

* Bachelor's degree in field relevant to the research (e.g., biology, cell biology, cancer biology).
* Advanced degree in field relevant to the research (e.g., biology, cell biology, cancer biology).

Experience:

* Experience in research.
* Molecular Biology techniques (i.e. quantitative real-time PCR, RNA and DNA isolation, transfection, Lentivirus mediated gene silencing, transformation, cloning).
* Biochemical techniques (i.e. immunoblots).
* Tissue Culture techniques (i.e. ex vivo cultures, primary cell isolation, transfection, infection, co-culture, three-dimensional modeling).
* Cell assays (i.e. adhesion, migration, invasion, proliferation, apoptosis, cytotoxicity).
* Cancer stem cell isolation and culture (human or mouse tumors)
* Flow cytometry.
* Microscopy (i.e. immunofluorescent analysis, wound healing assay, immunohistochemical analysis).
* Mouse in vivo models of cancer metastasis (i.e. intraperitoneal injections and dissections).
* Transgenic mouse models (i.e. breeding and genotyping).
* Mass spectrometry.

Preferred Competencies

* Strong Organizational skills.
* Problem-solving skills.
* Collaboration and independence.
* Attention to detail.
* Effective communication.
* Knowledge in cancer biology and role of microenvironment during cancer progression.
* Proficient in research techniques or methods (cell biology, translation, transcription, primary cultures, microscopy, cell assays, biochemical assays, molecular biology assays).
* Well versed in regulatory policies and procedures.
* Strong interest in and commitment to research goals of laboratory.
* Comfort working with a team.
* Flexible in changing research focus.
* Background contributing to research manuscripts, reports, or publications.
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Working Conditions

* Lab environment.
* Stand for extended periods.
* Use computer for extended periods.

Application Documents

* Resume/CV (required)
* Cover Letter (preferred)

When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.

Job Family

Research

Role Impact

Individual Contributor

FLSA Status

Non-Exempt

Pay Frequency

Biweekly

Scheduled Weekly Hours

40

Benefits Eligible

Yes

Drug Test Required

Yes

Health Screen Required

Yes

Motor Vehicle Record Inquiry Required

No

Posting Statement

Applicant Inquiry Form.Applicant Inquiry FormThe University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

Staff Job seekers in need of a reasonable accommodation to complete the application process should call or submit a request via Applicant Inquiry Form.

We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange.

All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: . Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.

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