Scientist II - Peptide Chemist

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Job description

Help us transform patients' lives.

We're here because we want to build the future and transform patients' lives for the better. At UCB, our people are our experiences and achievements, our passion and drive. That's why we're looking for talented individuals with diverse backgrounds and experiences - not just the best and brightest, but those who care about making a meaningful difference in the lives of patients. We promote an environment of diversity, openness, and respect where people can make valuable contributions.

An exciting journey lies ahead. Will you join us in pushing the boundaries of what's possible?

We are seeking a motivated Scientist II - Peptide Chemist to be an integral member of our Chemistry group, responsible for using our powerful peptide discovery platform to identify and engineer novel inhibitors of undruggable target proteins. The successful candidate will be a skilled experimentalist with deep knowledge of peptide chemistry and medicinal chemistry. The position will be based in Cambridge, MA.

You will contribute by:

• Working as an integral member of a broad team of scientists (including chemistry, biology, CADD, DMPK) to develop peptide drugs as part of our discovery programs.
• Independently designing drug-like peptide molecules utilizing medicinal chemistry knowledge, including property-based optimization, and an understanding of ADME, pharmacokinetics and optimal physicochemical properties.
• Developing and implementing new methods to advance our peptide drug discovery efforts.
• Designing the chemical synthesis for peptides, peptide modifications and peptide conjugates (e.g. using solid phase peptide synthesis and peptide arrays.)
• Ensuring optimal interaction, communication and providing regular updates on project status to the program leads and leadership team.
• Triaging screening hits to identify progressible chemical matter.
• Managing internal and external resources towards the delivery of drug candidates.

Interested? For this position, you'll need the following education, experience, and skills:

Minimum Qualifications:

• Ph.D. in organic chemistry, chemical biology, medicinal chemistry, or related field with 5+ years of experience, preferably within the biopharma industry.

Preferred Qualifications:

• Proficient in peptide chemistry design, synthesis, characterization, bioconjugation technology, and SAR analysis.
• Experience with medicinal chemistry drug discovery.
• Experience with chromatography and mass spectrometry data analysis, method development, strong familiarity and aptitude with LC and MS instrumentation, and MS Software.
• Experience functioning within a strong multi-disciplinary team and utilizing cross-functional information, such as ADME, DMPK, in vitro and in vivo data to drive drug design strategies.

Why you should apply:

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you'll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees - just as we do for the patients we serve. If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.

About us:

At UCB, we come together every day to work, laser-focused, on a simple question: How will this create value for people living with severe diseases? By putting patients at the heart of everything we do, our approach - from discovery to development to delivery - is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,600 employees and worldwide operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases. We are looking for people with passion and empathy who develop a real understanding of patient's needs and can deliver thoughtful solutions to decisionmakers across the heath care ecosystem.

Curious to know more? Please visit our website at

Where permitted, applicants for employment in the United States must have received or be willing to receive a full COVID-19 vaccination by the date of hire; or, alternatively, agree to be subject to weekly COVID-19 testing, subject to religious and medical exemptions and in accordance with applicable law.

UCB is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, national origin, religion, gender, age, marital status, disability, veteran status, sexual orientation, gender identity, or any other characteristic protect by law.

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