Scientist\/Sr. Scientist, Target ID & Validation

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Job description

Scientist /Senior Scientist Target ID & Validation

Job Scope & Purpose:

As a Scientist / Sr. Scientist at our client company, you will join an interdisciplinary team of highly creative and talented individuals whose vision is to improve patients' lives by expanding the space of RNA-targeted Therapies. You will have a key role in identifying and validating novel non-coding RNA targets. You will be a key team member responsible for optimizing the discovery platform in collaboration with our scientists, both hands-on and by leading junior scientists / research associates. You will have an opportunity to work with a diverse team of biologists, biochemists, chemists and bioinformaticians to support drug discovery programs for next wave of RNA therapeutics

Primary Job Responsibilities:

• Leverage your experience in target ID and validation and proprietary internal resources to systematically validate candidate targets generated by our diverse new target ID efforts.
• Develop functional assays, knock-down/KO and expression approaches tailored to our candidate targets to deliver high quality validated targets for drug discovery.
• Lead, mentor, and empower junior Associates
• Work effectively in a cross-functional capacity with, bioinformatics, biochemistry and chemistry teams to deliver high-quality results in an efficient manner.
• Collaborate and communicate across a diverse interdisciplinary research team.
• Keep detailed and organized records of experimental protocols and results.
• Contribute to multiple projects simultaneously and manage diverse team interactions.
• Contribute to daily lab management activities.
• Record, communicate and present experimental outcomes effectively across the organization.

Primary Job Requirements:

• Ph.D. in Biology, Molecular Biology, Cellular Biology, Genetics, or equivalent.
• 3-8 years of relevant experience required, with at least 2 years in industry preferred.
• Strong foundational knowledge of target ID and validation activities (functional screens, CRISPR/Cas9 approaches, shRNA, siRNA, etc).
• Strong scientific background in ncRNA and RBP biology.
• Proven track record of scientific innovation, as demonstrated by peer reviewed publications and/or presentations.
• Experience in designing, planning, and executing experiments independently is required.
• Proficient in mammalian cell line and primary cell culture and transfection.
• Experience with RNA biology-specific technologies.
• Experience in common molecular biology techniques such as RNA isolation, PCR/qPCR is required.
• Experience in common biochemical and immunological assays such as ELISA/MSD/Luminex, Western blot is required.
• Understanding in early-stage drug discovery process is required.
• Experience with automation and other high-throughput tools and instrumentation is a plus.
• Experience with FACS/Flow Cytometry and gene editing techniques such as RNAi-mediated transient gene knockdown or CRISPR/Cas9 is preferred.

About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

PROVEN SCIENTIFIC PLACEMENT™

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

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EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at or . - provided by Dice