Bioinformatics Scientist
GreenLight Biosciences, Inc.
2021-12-03 11:30:03
Medford, Massachusetts, United States
Job type: fulltime
Job industry: Science & Technology
Job description
ABOUT GREENLIGHT
GreenLight Biosciences is an integrated life sciences company developing safe and effective products that address critical problems facing plant health, human health, and animal health. Through scientific imagination and determination, we are developing products to create a future with a cleaner environment, healthier people, and a stronger food supply chain. At the core of the company's rapid growth is a proprietary platform for higher quality RNA production at a lower cost and faster speed than has ever been possible.
At GreenLight, we believe inclusion is the way forward. We celebrate the power of working together to address humanity's challenges, meet the needs of underserved populations, and push the boundaries of scientific discovery. Fueled by our aspiration for a true sense of belonging, our talented teams embody the principles of diversity and equality as we strive to bring food security, medicine, and healthcare to everyone-paving the way for a sustainable future. For more information, visit .
POSITION SUMMARY
GreenLight Biosciences is seeking an exceptional and motivated Bioinformatics Scientist to contribute within our Data Science and Bioinformatics team. You will closely partner with GreenLight's scientists to combine your knowledge of Genomics, Bioinformatics, Machine Learning and Biological Computing to efficiently execute a comprehensive suite of analyses that will impact our Human and Plant Health efforts. In this role, the Bioinformatics Scientist is expected to mine and engineer hypotheses from large, complicated data sets from different sources (genomics, proteomics, assay data, RiboSeq, etc.) to get a more holistic understanding of complex biological phenomena. The ideal candidate has experience working in a mammalian computational biology setting with biological datasets including but not limited to NGS, cell and other assay data, with experiences in algorithm design and running routine bioinformatics analyses.
MAJOR RESPONSIBILITIES
- Design automated bioinformatics workflows and novel algorithms to derive actionable biological insights/conclusions from a variety of biological data sets, with a focus on mammalian data
- Design and apply data processing models to large-scale multi-omics eukaryotic datasets (RNA, Protein) by combining existing public and commercial tools with innovative solutions
- Perform analyses that establish structure-function relationships in mammalian protein and RNA datasets
- Perform complex statistical analyses and architect / train ML models on large biological datasets such as NGS-derived and others to formulate/validate hypotheses
- Translate data into biological knowledge, and communicate with appropriate visualizations broadly to diverse audiences
- Collaborate with other scientific staff members within and outside the R&D group, including academic collaborators, external consultants, and scientists, to plan and execute high throughput projects with large and diverse datasets
- Document results of analyses and investigations in a reproducible manner
PROFESSIONAL EXPERIENCE / QUALIFICATIONS
- Scientific background with a PhD degree in Bioinformatics, Computational Biology, Data Science, Machine Learning, Statistics, Genetics or a related biological computation-centric field
- A minimum of >=2 years of post-graduate experience in the fields of protein structure/function analysis, RNA/Protein sequence analysis, genomics, bioinformatics, machine learning, algorithm development, molecular biology, sequencing or related computational biology/bioinformatics areas
- A minimum of >=2 years omics experience specifically with data from High-throughput techniques for different biological phenomena such as RNA-Seq, Shape Seq, Mass Spec, RiboSeq, ATAC-Seq, sRNA-Seq, Whole Exome Sequencing etc.,
- Strong coding skills in Strong capability in and deep experience with R as a toolset for data access, data cleaning, statistical analysis, and visualization
- Solid, demonstrable experience developing algorithms for solving biological problems. A biology-centric and data-oriented thought process.
- Scientific data analysis expertise, complemented by strong visualization and presentation skills
- Experience with high-performance computing environments including cloud infrastructures such as Azure, AWS or Google Cloud (Azure preferred)
- Experience with JIRA, Trello, Confluence and GitHub
- Excellent communication and interpersonal skills to translate biologists/project team's scientific questions into analytical strategies and methods
- Demonstrated ability to present complex results, both verbally and in writing, to bioinformatics and non-bioinformatics audiences of all levels is critical
- Must maintain a HIGH level of ownership and see assignments through to completion based on agreed upon deadlines. Accurately estimate timelines and communicate progress
- Must be independently driven, results-oriented and a quick learner
- Must possess team working ability, learning agility, scientific curiosity with a problem-solving mindset, organizational skills and an enthusiastic, collaborative spirit
PREFERRED QUALIFICATIONS
- 2+ years relevant experience in the pharmaceutical (vaccines, antibodies etc.) industry
- Expertise in advance data science techniques and tools, machine learning, unsupervised learning and statistical analysis as well as common machine learning software (e.g., scikit-learn, Tensorflow, Keras, etc.)
- Enthusiasm and interest in unlocking novel areas of potential commercial value in a startup environment
Greenlight Biosciences Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.
GreenLight requires proof of COVID-19 vaccination for its employees consistent with OSHA guidelines.