Research Scientist - Bioanalytical LC-MS/MS

---

Job description

• • As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment.

PPD is a leading global contract research organization providing comprehensive, integrated drug development, laboratory and lifecycle management services. At PPD, we are passionate, deliberate, and driven by our purpose- to improve health!

PPD Laboratories offers the most comprehensive set of laboratory services available in the industry and continues to deliver innovative solutions to our clients through our collaborative approach, including PPD® Laboratories FSP. PPD® Laboratories FSP is a unique partnership that allows our clients to leverage the experience of our PPD staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits/advantages of being a part of PPD.

The Department of Clinical Biomarker Immunoassay & Mass Spectrometry (CBIMS) in Translational Medicine at our client site in Princeton, NJ is seeking a candidate to provide expertise and laboratory support for the quantitative analysis of biomarkers in drug discovery and development.

The major responsibility for this position is to develop and execute LC-MS based methods in support of quantitative biomarker (small molecules, peptides and proteins, etc) analysis, including assay development, validation, troubleshooting and sample analysis for non-clinical and clinical studies from different therapeutic areas. You will also report study sample results to clients following the department policies and procedures, and communicate laboratory results and findings in cross-disciplinary project team and department meetings. You must be highly motivated, organized, with excellent communication skills (oral and written), detail oriented, and most importantly a good team player.

PPD Defining Principles:

- We have a strong will to win - We earn our customer's trust - We are gamechangers - We do the right thing - We are one PPD -

If you resonate with our five principles above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world's most urgent health needs, then please submit your application - we'd love to hear from you

*LI-SW1

Qualifications:

Education and Experience:

• Bachelor's degree or equivalent and relevant formal academic / vocational qualification
• Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 8+ years).
• In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

• Proven ability in technical writing skills
• Good knowledge of LC-MS instrumentation for small and large molecule quantitation; experienced in both triple quadrupole MS and high resolution mass spectrometry (HRMS) platforms.
• Hands on experience on Thermo's Q Exactive, Sciex's Triple TOF 6600+ or Bruker's TimsTOF Pro platforms is desirable.
• Experience of immuno-capture LC-MS assay workflow, including immuno-capture with bead or cartridge formats, enzymatic digestion, and basic knowledge of ligand-binding assay (LBA) is a plus.
• Capability of performing complex and multiplex biomarker LC-MS assay development in biological matrices.
• Familiar with Skyline, Spectronaut™ and other advanced protein analysis software for targeted proteomics is desirable.
• Knowledge and hands on experience in proteomics is a plus.
• Ability to keep accurate and timely documentation per departmental guidelines, timely document and communicate abnormal laboratory observations.
• Possess excellent communication and organizational skills in a cross-functional environment.
• Ability to work in a collaborative work environment with a team
• Proven problem solving and troubleshooting abilities
• Ability to independently optimize analytical methods
• Time management and project management skills

Working Environment:
PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

• Able to communicate, receive, and understand information and ideaswith diverse groups of peoplein a comprehensible and reasonable manner.
• Ableto work upright and stationary and/or standingfor typical working hours.
• Able to lift and move objects up to 25 pounds
• Able to work in non-traditional work environments.
• Able to use and learn standard office equipment and technologywith proficiency.
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.