Research Technician/Technologist - Cherepanova Lab

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Job description

At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day.

We all have the power to help, heal and change lives - beginning with our own. That's the power of the Cleveland Clinic Health System team, and The Power of Every One.

Job Title
Research Technician/Technologist - Cherepanova Lab

Location
Cleveland

Facility
Cleveland Clinic Main Campus

Department
LRI Cardiovascular and Metabolic Sciences-Research Innov and Educ

Job Code
D99981

Shift
Days

Schedule
8:00am-4:30pm

Job Summary
Putting patients first means a little more at Cleveland Clinic. Our reputation for cutting-edge medicine was built through a patient-centric approach that all of our caregivers play a role in. You can make a difference as a Research Technician or Research Technologist as part of the Lerner Research Institute. Research Technicians and Research Technologists who thrive in this role are able to perform laboratory techniques, analyze and monitor research protocols, and assemble experimental results for review by various staff. Teamwork, dedication and innovation are keys to success in this role. Exceptional care requires exceptional caregivers from the very first moment they contact Cleveland Clinic.

Job Details

Dr. Cherepanova's Lab in the Department of Cardiovascular and Metabolic Sciences is currently seeking a Laboratory Specialist. The incumbent participates in research to understand cellular and molecular mechanisms that contribute to development of cardiovascular disease. The incumbent is responsible to help with the routine lab operation, do ordering in the Infor Lawson system, as well as for managing mouse colony. The latter includes maintaining meticulous records of mouse inventories, breeding, genotyping, and maintaining an electronic database, as well as writing IACUC animal protocols.

This position also includes immunohistochemical processing, embedding, sectioning, and analysis of IHC staining of mouse and human tissues; immunohistochemical analysis; and performance of computer morphometric analyses of stained vascular histological preparations. Other duties include assistance in studies involving use of recombinant DNA techniques, including real-time PCR, PCR genotyping, promoter analyses, gene cloning, site-directed mutagenesis, and chromatin immunoprecipitation assays.

The individual also works with all students, fellows, post-docs, and other members of the lab to assist in conducting all aspects of animal experiments. The position requires coordinating research projects and logistics with other lab members; compliance with Clinic, Federal, and State policies and procedures; consulting with the Principle Investigator as needed and helping oversee laboratory equipment and supplies required for operation of the laboratory.

Responsibilities:

• Performs laboratory techniques procedures required for experimental studies including planning, organizing, performing and monitoring daily project protocols.
• Collects, prepares and maintains required research documentation, including informed consent records, case records, clinical notes and medical reports.
• Reports and assists with the management of protocol deviations, adverse events and other project-related issues, which could include assisting with establishing and scheduling of various procedures.
• Prepares reagents, purifies chemicals using chromatography, distillation, etc., identifies, separates and quantifies various substances.
• Accumulates data from analyses, prepares charts, graphs, statistical tables for presentation to Research Staff Supervisor for final analysis and preparation for publication, grant proposals and applications for research funds.
• Responsible for the assistance in general maintenance and upkeep of the lab.
• Assists in ordering and purchasing supplies as directed from the supervisors.
• Gathers information on new equipment necessary in the lab and recommends purchases.
• Other duties as assigned.

Education:

• Knowledge of basic laboratory procedures, techniques, methods and analysis sufficient to perform a variety of research protocols; basic knowledge of quantitative and statistical methods normally attained through completion of a Bachelor's Degree in a biological science major or a related field of study for Technician level.
• Or Bachelor's degree in biological sciences or related field and knowledge of laboratory maintenance and equipment, or Master's degree in biological sciences or related field and one year experience for Technologist level.

Complexity of Work:

• Requires critical thinking skills, decisive judgment and the ability to work with minimal supervision.
• Must be able to work in a stressful environment and take appropriate action.

Work Experience:

• A minimal amount of applicable experience may be considered to offset up to one year of the college degree requirements for Technician level (after selection and placement into this position, up to six months of on-the-job training required to become familiar with laboratory techniques, procedures and research protocols).
• OR of two years of experience in a research or related laboratory environment for Technologist level.
• Experience in handling mice and molecular biology techniques (PCR, western blotting, immunostaining and microscopy) is strongly preferred.
• Ideal applicants will have working knowledge of Microsoft Office.

Physical Requirements:

• Visual acuity. The ability to distinguish colors.
• Manual dexterity to handle specimens and repair equipment.
• May be required to stand for long periods of time.
• Light lifting may be required.
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• Follows standard precautions using personal protective equipment as required.

Keywords: PCR, western blotting, immunostaining, microscopy, mouse handling

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our employees and applicants for employment in our tobacco free and drug free environment. All offers of employment are followed by testing for controlled substance and nicotine. Job offers will be rescinded for candidates for employment who test positive for nicotine. Candidates for employment who are impacted by Cleveland Clinic Health System's Smoking Policy will be permitted to reapply for open positions after 90 days.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility.

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Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities