Associate Scientist, Custom & Process Analytics

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Job description

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS's continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.

The Custom & Process Analytics (CPA) department is seeking an Associate Scientist to execute development activities for novel analytical methods and strategies in early phase cell therapy pipeline projects. The CPA team is responsible for developing and executing phase-appropriate analytics for early stage cell therapy programs and identifying novel analytical technology platforms that will improve the throughput, turnaround time, and/or resolution of product quality attributes. Individuals in this role will interact cross-functionally with process and analytical development organizations to align analytical strategies and timelines, develop and execute custom analytical needs, and deliver high quality/high-throughput analytics to support early process development. Interaction with junior scientists will including technical wet-lab and analytical training and review of development and routine analytical results.

The Associate Scientist will also independently support custom method development , execution and analytical routine testing in the lab. Successful candidates will have a strong foundation in immunology and a variety of immunological methods. This role is highly collaborative and requires a demonstrated ability to coordinate projects with cross-functional teams and independently design and execute studies to meet project goals.

DUTIES AND RESPONSIBILITIES

• Independently develop polychromatic flow cytometry panels for immediate implementation into pipeline development programs
• Analytical support of ongoing process development studies with developed analytical methods
• Evaluation of novel reagents, technologies, and instrumentation to increase throughput and efficiency of process analytics
• Assist and train users within the department on method execution, data analyses, and proper use of instrumentation
• Transfer of developed flow cytometry method onto established automation system
• Titrate and maintain antibody stocks, as needed

QUALIFICATIONS AND EDUCATION REQUIREMENTS

• Education: A Bachelor's with 6 years of experience or Master's with 4 years of experience in a scientific discipline
• Proven ability to work in a high paced team environment, meet deadlines, & prioritize work on multiple projects.
• Strong foundation in immunology and/or cell biology including experience with primary immune cells.
• Demonstrated experience with development and execution of polychromatic (13-plus color) flow cytometry panels
• Thorough and demonstrated understanding of flow cytometry instrumentation and software such as Flow Jo, FACS Diva, and FCS Express

PREFERRED QUALIFICATIONS

• Experience with rapid delivery of novel analytics in support of pipeline development
• Thorough understanding of immunology and cell-based assays as applied to the cell therapy field
• Experience with functional assays using primary human T-cells
• Assay development (flow cytometry, bead-based multiplexed platforms, ELISA, cell killing assays)
• Experience with cellular cryopreservation protocols
• Experience with migrating established assays to automated liquid handlers
• Successful track record of prioritizing work across multiple projects

WORKING CONDITIONS

• Work will be conducted in office and laboratory environments with a mix of natural and LED lighting with low level background noise Personal protective equipment (PPE) must be worn at all times when in the laboratory, including but not limited to lab coats, protective eye gear, and disposable gloves. Work environment may include extended time working in biosafety cabinets and liquid nitrogen storage containers. Physical activity involves moving between wet-lab stations to execute experimental plans, moving up and down stairs or elevators to access equipment or materials on other floors, and may involve lifting containers (usually
• 15% time seated desk work with ergonomic working spaces and sit/stand desks; 85% time in laboratory or meetings.
• This job description is intended to describe the general nature and level of work being performed by the person assigned to this position. The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.
• This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.

If you want to challenge yourself, accelerate your career, and give new hope to patients, there's no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients' lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.

BMSCART

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

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