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Bioinformatics Analyst

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Fred Hutchinson Cancer Research Center

2021-12-03 07:32:46

Job location Seattle, Washington, United States

Job type: fulltime

Job industry: Science & Technology

Job description

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The HIV Vaccine Trials Network (HVTN) is the world's largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS, through clinical research studies. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 efficacy trials of vaccines and antibodies to prevent infection and COVID-19 disease, to ensure rapid and thorough evaluation that can support approval and dissemination of the interventions.

The Bioinformatics Analyst will provide analytical and programming support as part of the Bioinformatics Core and Biosequence Analysis Unit of the HIV Vaccine Trials Network and Coronavirus Prevention Network. The field of vaccine research is increasingly relying on the use of high-throughput genetic and proteomic data to make scientific advancements, and the HVTN and CoVPN are looking for a person with the skills, drive and curiosity to help us overcome these epidemics. This position has responsibilities for both data analysis and programming support for our data and information infrastructure. This is an applied position, where computer programming and data analytics are toolkits for solving scientific problems, typically involving viral sequence data integrated with clinical and immunology data. The ideal candidate will have a grounded understanding of statistics/data analysis and software development - especially high-performance computing - as well as a deep scientific curiosity about applying software and data analysis to the field of vaccine research.

Responsibilities

* Work with scientific and analytic collaborators to define analysis and data requirements
* Manage and process multifarious types of study data
* Developing software processes and pipelines for data management, data processing and analysis
* Generating data visualizations and reports of analysis results
* Software development for long-term data-management, analysis, and infrastructure projects
* Presenting scientific results and contributing to scientific papers
* Work collaboratively with both our local team and a global network of scientists
* Perform other responsibilities as required

Qualifications

MINIMUM QUALIFICATIONS:

* Bachelor's degree in the quantitative or physical sciences, or equivalent experience
* 2-4 years of experience with scientific computing, ideally in the domain of biomedical/scientific research and genomics/proteomics
* 2+ years of experience programming in R and/or Python, ideally both
* 2+ years of experience with high-performance computing (i.e., the development of multi-core or multi-threaded computational jobs)
* Strong analytical abilities and problem-solving skills
* Experience with inferential statistics and machine learning
* Experience in data management and developing data-processing pipelines
* Knowledge of databases, including relational databases and no-SQL databases, e.g., MongoDB
* A solid understanding of high-level programming concepts, data structures and algorithms
* Familiarity with software development best practices (e.g., unit testing, version control)
* Excellent written and oral communication skills

PREFERRED QUALIFICATIONS:

* Master's degree or greater in the quantitative or physical sciences
* Competency in other programming languages, such as Java and/or C++
* 2-4 years of experience working with genetic/proteomic data, ideally in the field of pathogen genomics
* Experience working with lab assay data
* Experience working with reproducible research tools and processes
* Experience with containerization (especially Docker) and virtual machines
* Proficiency in working with and developing software in Linux-based operating systems

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations. As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at or by calling .

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